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Process Ball Milling

High energy ball milling as green process to vitrify ,In this study, the suitability of high-energy ball milling was investigated with the aim to vitrify tadalafil and improve its bioavailability. To achieve this goal, pure TD as well as binary mixtures composed of the drug and soluplus were coprocessed by high-energy ball milling. modulated differential scanning calorimetry and x-ray powder diffraction demonstrated that

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